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These include: Inappropriate dosing or frequency Lack of proper diagnosis and monitoring Non-sterile injection technique increasing infection risk Absence of medical supervision for adverse reactions Financial cost without clinical benefit Patients should report any suspected adverse reactions to B12 injections via the MHRA Yellow Card scheme

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Psychopharmacology (Berl) 218, 2011

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Of these, 9% of patients had Grade III or IV chondral lesions and were under 50 years old, meeting conservative indications for cartilage repair surgery

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